Paxil (Paroxetine HCI)


Central nervous system agent


Antidepressant


Aocial Anxiety disorder,Depression, obsessive-compulsive disorder, Panic Disorder, social Anxiety disorder.


20-60 mg/day, before or after meals.


Category C


Somnolence, dizziness, Insomnia, agitation, tremor, Anxiety, decreased appetite, nausea, Diarrhea, Constipation, dry mouth, paresthesia, vasodilation, lump or tightness in throat, dyspepsia, ejaculatory disturbances, myopathy, diaphoresis.




Pregnancy Risk Categories defined:

A: Studies in pregnant women failed to show a risk to the fetus in the first trimester - with no evidence of risk in the later trimesters.

B: Animals studies indicate no adverse effect to the fetus, but there are no adequate, clinical studies in pregnant women.

C: Animal studies have shown an adverse effect on the fetus, but there are no adequate, clinical studies in humans. Despite potential risks, the drug may be useful in pregnant women.

D: There is evidence of risk to the human fetus, but the potential benefits of use in pregnant women may be acceptable, despite potential risks.

X: Studies in animals or humans show fetal abnormalities, or adverse reaction reports indicate evidence of fetal risk. Warning: the risks involved clearly outweigh any potential benefit from using the drug in pregnant women, regardless of trimester.

NR: Not rated (i.e., no information available at this time as to the potential risks or benefits).