Nuclear scan (Isotope scan) Normal uptake, distribution, and excretion of the radionuclide by the targeted organ or tissue No anbormality of structure or function in the targeted organ A gamma camera or scintillation scanner records the radioactive emissions, these emissions are converted by computer to image that correspond to the location, distribution, concentration of the radionuclide in the target organ or tissue. To assess the physiologic function To assist in the localization and diagnosis of abnormality in a designated organ or tissue Organ atrophy or fibrosis Cyst Tumor Metastatic lesions Inflammation Abscess Congenital defect Obstruction of a duct Hyperactivity of function Hematoma Traumatic disruption of tissue Vascular obstruction Ischemia or necrosis of tissue Failure to follow specific pretest dietary or medication restrictions Recent intake of iodine