Filariasis


Elephantiasis




Abnormal
  • The lymph gland system helps clear both infections and fluids from the body.  Elephantiasis is a disease that occurs when various parasitic worms infect the lymph glands.  These parasitic worms are as follows:
    1. Wuchereria bancrofti -- found and transmitted in the tropics and subtropics
    2. Brugia malay -- found in South India, Sri Lanka, Southeast Asia, South China, the northern coast of China, and South Korea
    3. Brugia timori -- found in the southeastern islands of Indonesia.  These organisms are transmitted to humans by mosquito bites in a form called microfilariae

  • Acute infection:
    1. Fever
    2. Pain in testicles
    3. Pain above testicles
    4. Enlarged groin lymph nodes
  • Chronic:
    1. Massively swollen legs (elephantiasis)
    2. Swelling in scrotum
    3. White urinary discharge
    4. Swollen liver
    5. Swollen spleen
    1. Coughing or wheezing
    2. Fever

  • Microfilariae in the blood
  • Serologic testing sometimes helpful
  • Tropical pulmonary eosinophilia
    1. Increased blood eosinophils
    2. High filarial antibody titers
    3. High IgE levels
    4. Chest X-Ray shows increased bronchovascular markings

  • Diethylcarbamazine
  • Surgery for massive leg swelling (elephantiasis) with a fluid shunting procedure