Diflucan (Fluconazole) Systemic Anti-infective Anti-fungal agent Vaginal, esophageal, urinary, systemic, Yeast Infection, cryptococcal meningitis. Doses are tablet, suspension, or IV. (Adults) Adjust according to patient response. Vaginal Yeast Infection: Single 150 mg tablet. Other Yeast Infections: 200mg on 1st day, followed by 100 mg once daily. Continue treatment for >2 weeks. Esophageal Yeast Infection 200 mg on 1st day, followed by 100mg once daily for minimum of 3 weeks. Systemic Yeast Infection: Optimal dosage not established; max. 400 mg/day. UYI, peritonitis: 50 to 200 mg/day. Cryptococcal meningitis: 400 mg on 1st day, followed by 200 to 400 mg once daily. Duration of treatment is 10 to 12 weeks before or after meal. Category C Nausea, headache, skin rash, vomiting, abdominal pain, diarrhea. More frequent in AIDS. Pregnancy Risk Categories defined: A: Studies in pregnant women failed to show a risk to the fetus in the first trimester - with no evidence of risk in the later trimesters. B: Animals studies indicate no adverse effect to the fetus, but there are no adequate, clinical studies in pregnant women. C: Animal studies have shown an adverse effect on the fetus, but there are no adequate, clinical studies in humans. Despite potential risks, the drug may be useful in pregnant women. D: There is evidence of risk to the human fetus, but the potential benefits of use in pregnant women may be acceptable, despite potential risks. X: Studies in animals or humans show fetal abnormalities, or adverse reaction reports indicate evidence of fetal risk. Warning: the risks involved clearly outweigh any potential benefit from using the drug in pregnant women, regardless of trimester. NR: Not rated (i.e., no information available at this time as to the potential risks or benefits).