Buspar (Buspirone HCI)


Central nervous system agent


Antianxiety agent


Management of anxiety disorders or short-term relief of symptoms of anxiety.


Adults: Initially 7.5 mg twice daily. May increase dosage by 5 mg/day at 2- to 3-day intervals if necessary. Maintenance dose is 20 to 30 mg/day in divided doses. Maximum dose is 60 mg/day. Take before or after meals.


Category B


Dizziness, nausea, headache, nervousness, excitement, and light-headedness.



Pregnancy Risk Categories defined:

A: Studies in pregnant women failed to show a risk to the fetus in the first trimester - with no evidence of risk in the later trimesters.

B: Animals studies indicate no adverse effect to the fetus, but there are no adequate, clinical studies in pregnant women.

C: Animal studies have shown an adverse effect on the fetus, but there are no adequate, clinical studies in humans. Despite potential risks, the drug may be useful in pregnant women.

D: There is evidence of risk to the human fetus, but the potential benefits of use in pregnant women may be acceptable, despite potential risks.

X: Studies in animals or humans show fetal abnormalities, or adverse reaction reports indicate evidence of fetal risk. Warning: the risks involved clearly outweigh any potential benefit from using the drug in pregnant women, regardless of trimester.

NR: Not rated (i.e., no information available at this time as to the potential risks or benefits).